Table 4. Performance summary and characteristics of the FilmArray ME panel and CSF culture in bacteria and yeast detection.
| Pathogen identified | OPA (%) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Kappa |
|---|---|---|---|---|---|---|
| E. coli K1 | 89.7 | 60 | 92.1 | 37.5 | 96.7 | 0.408 |
| H. influenzae | 98.5 | 0 | 100 | 0 | 98.5 | 0 |
| L. monocytogenes | 98.5 | NA | 98.5 | 0 | 100 | 0 |
| N. meningitidis | 98.5 | NA | 98.5 | 0 | 100 | 0 |
| S. agalactiae | 95.6 | 100 | 95.4 | 50 | 100 | 0.646 |
| S. pneumoniae | 92.7 | 80 | 93.7 | 50 | 98.3 | 0.577 |
| Cr. neoformans/C. gattii | 98.5 | 100 | 98.5 | 50 | 100 | 0.66 |
OPA, overall percentage of agreement; PPV, positive predictive value; NPV, negative predictive value.