Table 1. Basal characteristics and outcomes of patients with and without low skeletal muscle mass.
| Variable | Non-low skeletal muscle mass (N=95) | Low skeletal muscle mass (N=421) | P |
|---|---|---|---|
| Age, years | 64.8±14.4 | 68.7±14.0 | 0.020 |
| Male | 54 (56.8) | 289 (68.6) | 0.028 |
| BMI (kg/m2) | 23.7±3.3 | 21.1±4.1 | <0.001 |
| SMI (cm2/m2) | 57.5±15.1 | 33.4±10.1 | <0.001 |
| APACHE II | 15.0±6.8 | 16.1±6.9 | 0.181 |
| SOFA | 8.2±4.4 | 8.2±4.0 | 0.999 |
| CCI | 4.2±2.5 | 4.3±2.2 | 0.808 |
| Multiple vasopressor use | 71 (74.7) | 339 (80.5) | 0.207 |
| Renal replacement therapy | 28 (29.5) | 126 (29.9) | 0.903 |
| Lactate on admission | 4.7±18.9 | 4.2±17.8 | 0.827 |
| Infection source | |||
| Respiratory | 81 (85.3) | 373 (88.6) | 0.366 |
| Abdominal | 9 (9.5) | 30 (7.1) | 0.434 |
| Urinary tract | 14 (14.7) | 49 (11.6) | 0.405 |
| Soft tissue | 8 (8.4) | 20 (4.8) | 0.154 |
| Rehabilitation | 52 (54.7) | 215 (51.1) | 0.518 |
| Ventilator day | 26.6±34.1 | 24.9±39.6 | 0.772 |
| Hospital stay | 44.4±45.4 | 54.8±63.0 | 0.065 |
| ICU stay | 17.4 ±23.4 | 19.3±23.9 | 0.492 |
| In-hospital mortality | 24 (25.3) | 138 (32.8) | 0.154 |
| Discharge to home | 56 (58.9) | 166 (39.4) | 0.001 |
| 6-month mortality | 25 (26.3) | 189 (44.9) | 0.001 |
| 1 year mortality | 31 (32.6) | 211 (50.1) | 0.002 |
Values are expressed as mean ± standard deviation or n (%). BMI, body mass index; SMI, skeletal muscle index; APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment; CCI, Charlson Comorbidity Index.