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. 2019 Oct 15;93(21):e01150-19. doi: 10.1128/JVI.01150-19

FIG 7.

FIG 7

Frequency of stalk-reactive ASCs in mice immunized with Flublok or Flucelvax. (A to E) Seven- to 8-week-old female BALB/cJ mice were immunized subcutaneously with 50 μl of vaccine (Flublok [n = 5] or Flucelvax [n = 5]) plus 10 μg poly(I·C) in PBS. Mice were sacrificed at day 10 postimmunization, spleen and draining lymph nodes were collected, and ELISpot assays were performed. Results are expressed as a percentage of total IgG ASCs in the given organ. (A) Percent IgG vaccine-reactive ASCs in the spleen and lymph nodes. (B) Percent IgG H1N1 full-length HA-reactive ASCs in the spleen and lymph nodes. (C) Percent IgG H1N1 HA stalk-reactive ASCs in the spleen and lymph nodes. (D) Percent IgG H3N2 full-length HA-reactive ASCs in the spleen and lymph nodes. (E) Percent IgG H3N2 HA stalk-reactive ASCs in the spleen and lymph nodes.