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FcγR SNPs (FCGR2A-intron13-645-G/A [rs2165088], FCGR2B-exon5-523-G/A [rs6665610], and FCGR2B-intron14-352-T/G [rs6666965]) modified the association of Fc effector functions (ConS gp140 ADCP score and FcγRIIa binding) with HIV-1 acquisition risk. (A and B) ConS gp140 ADCP score (A) and ConS gp140 FcγRIIa binding (B). On each panel, distributions of Fc effector functions were plotted according to case/control HIV infection outcome status and genotype groups.
