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Crb3 overexpression reduces AAV transduction. (A) qRT-PCR analysis of Crb3 expression in Scr and Crb3 OVX cells. (B to D) Transduction of Scr and clonal Crb3 OVX cells with AAV1 (B), AAV2 (C), and AAV9 (D) vectors packaging CBA-luciferase. A two-tailed unpaired t test was used (*, P < 0.05; **, P < 0.01; ***, P < 0.005).
