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. 2019 Oct 22;2019(10):CD005015. doi: 10.1002/14651858.CD005015.pub4

Neubauer 1984.

Methods
  • Study design: parallel RCT

  • Duration of study: July 1980 to September 1981

  • Duration of follow‐up: 18 months

Participants
  • Country: Germany

  • Setting: single centre

  • Inclusion criteria: kidney transplant recipients

  • Number: 38 (numbers per group not reported)

  • Mean age ± SD (years): not reported

  • Sex (M/F): not reported

  • Exclusion criteria: SCr > 0.16 mmol/L, hypercalcaemia or systemic disease

Interventions Treatment group
  • 1,25 dihydroxyvitamin D3 (oral): 0.25 µg/d


Control group
  • Placebo


Co‐interventions
  • Not reported

Outcomes
  • SCr

  • BMD by DEXA at radius

Notes
  • Funding source: Hoffman La Roche provided medication

  • Trial registration: not applicable as published before end of 2005

Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information to permit judgement
Allocation concealment (selection bias) Unclear risk Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Not blinded
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Insufficient information to permit judgement
Incomplete outcome data (attrition bias) 
 All outcomes High risk 10/38 participants did not complete study
Selective reporting (reporting bias) High risk Patient‐centred outcomes not reported in sufficient detail to include in meta‐analysis
Other bias Unclear risk Insufficient information to permit judgement