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. 2019 Oct 22;2019(10):CD005015. doi: 10.1002/14651858.CD005015.pub4

Psimenou 2002.

Methods
  • Study design: active comparator, open‐label, parallel RCT

  • Duration of study: not reported

  • Duration of follow‐up: 12 months

Participants
  • Country: Greece

  • Setting: single centre

  • Inclusion criteria: kidney transplant recipients

  • Number: treatment group (23); control group (20)

  • Mean age ± SD (years): not reported

  • Sex (M/F): not reported

  • Exclusion criteria: not reported

Interventions Treatment group
  • Calcitonin (intranasal): 200 IU/d periodically for 1.5 months


Treatment group
  • Etidronate (oral) 200 mg/d for 15 days every 3 months


Co‐interventions
  • Not reported

Outcomes
  • BMD (lumbar spine, femoral neck, forearm)

  • Treatment‐related hypocalcaemia

  • Adverse events

Notes
  • Abstract‐only publication. Full‐text publication not identified

  • Funding source: not reported

  • Trial registration: not applicable as study published before end of 2005

Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information to permit judgement
Allocation concealment (selection bias) Unclear risk Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Unblinded study. Interventions given by different routes
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Insufficient information to permit judgement
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Insufficient information to permit judgement
Selective reporting (reporting bias) High risk Patient‐centred fracture, death and graft outcomes not systematically captured or reported
Other bias Unclear risk Insufficient information to permit judgement