FIG 4.
IL-17C promotes the recruitment of neutrophils during acute S. pneumoniae pneumonia. WT and Il-17c−/− mice were intranasally infected with S. pneumoniae (∼8 × 106 CFU per mouse). Numbers of viable bacteria (CFU) were determined in BAL fluids (A). Numbers of total cells (B), neutrophils (C), macrophages (D), and lymphocytes (E) were determined in cytospin preparations. Data are shown as the means ± standard deviations (n = 6 per group). **, P < 0.01, for a comparison of results in infected Il-17re−/− mice to those in infected WT mice.