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. 2019 Oct 15;11:276. doi: 10.3389/fnagi.2019.00276

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Copyright © 2019 Liu, Li, Chen, Wei, Hu, Yu, Ruan, Zhou, Pan, Li, Luo and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Regional homogeneity differences among NC, FOG–, and FOG+ within the bilateral caudate. (A) Bilateral caudate. (B) F-map of ANCOVA analysis of the three groups, corrected by GRF with voxel p < 0.05, threshold of F > 3.84 and cluster size >1566 mm³. (C) FOG+ subjects showed higher ReHo within the left caudate than did FOG– and NC. Post hoc two-sample t-tests on FOG+ and NC (D,G), FOG– and NC (E,H), and FOG+ and FOG– (F,I). The T-map in (E) was with a threshold of an uncorrected voxel p < 0.05, (D,F) were corrected by GRF with voxel p < 0.05, threshold of T > 2.00 and cluster size >486 mm³. L/R, eft/right hemisphere; NC, normal controls; FOG+/FOG–, Parkinson’s disease with/without freezing of gait.