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. 2019 Oct 15;9:1015. doi: 10.3389/fonc.2019.01015

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Copyright © 2019 Buderath, Schwich, Jensen, Horn, Kimmig, Kasimir-Bauer and Rebmann.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Association of high sPD-L1 levels with reduced overall survival (OS) and progression-free survival (PFS) in platinum-sensitive patients. Platinum-sensitive EOC patients with high sPD-L1 serum levels (>6.4 pg/mL) had a reduced (A) overall survival (OS; p = 0.035) and (B) progression-free survival (PFS; p = 0.081) compared with platinum-sensitive patients with low sPD-L1 levels (<6.4 pg/ml). Time was calculated from blood sampling to event (death/progression) or last follows up. Dotted line indicates the median survival time of EOC patients.