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. 2019 Oct 15;10:1200. doi: 10.3389/fphar.2019.01200

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Copyright © 2019 Shi, Ren, Jia, Tang, Guo, Ni and Shi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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OI-related candidate mutations in COL1A1 and COL1A2. (A) OI-related candidate mutations in COL1A1 (“*”: currently unknown). (B) OI-related candidate mutations in COL1A2 (“*”: currently unknown). (C) Localization of variants c.G2332T (p.G778C) and c.G2341T (p.G781C) in COL1A2 protein sequence. Predicted pathogenic variations are represented in bold font (Eight orange rectangles with black border denote eight lethal spaces).