Table 1.
Baseline characteristic of studied population
| Valid N at baseline | Mean (SD) or count (%) | Delirium mean (SD) count (%) | No delirium mean (SD) count (%) | Mortality 3 months post-stroke (univariate analysis p value) | Mortality 12 months post-stroke (univariate analysis p value) | |
|---|---|---|---|---|---|---|
| Total | 750 | |||||
| Delirium | 203 (27%) | 547 (73%) | < 0.001 | < 0.001 | ||
| Mean CTD | 136 | 11.2 (5.9) | 11.2 (5.9) | – | 0006 | < 0.001 |
| Mean DRS | 203 | 18.2 (4.5) | 18.2 (4.5) | – | < 0.001 | < 0.001 |
| Duration time | 203 | 4.2 (2.3) | 4.2 (2.3) | – | > 0.05 | 0.044 |
| Mean age (SD), years | 750 | 71.8 (13.1) | 77.0 (10.7) | 69.8 (13.4) | < 0.001 | < 0.001 |
| Hemorrhagic stroke | 750 | 52 (7%) | 24 (12%) | 28 (5%) | > 0.05 | > 0.05 |
| Ischemic stroke | 750 | 650 (87%) | 170 (84%) | 480 (88%) | > 0.05 | > 0.05 |
| TIA | 750 | 48 (6%) | 9 (4%) | 39 (7%) | > 0.05 | > 0.05 |
| Gender (male) (%) | 750 | 352 (47%) | 84 (41%) | 268 (49%) | > 0.05 | > 0.05 |
| Cerebellar stroke vs hemispherical/brainstem | 735 | 73 (10%) | 8 (4%) | 65 (12%) | > 0.05 | > 0.05 |
| Left vs. right hemisphere | 661 | 364 (55%) | 91 (45%) | 273 (50%) | > 0.05 | > 0.05 |
| Education (SD), years | 658 | 11.4 (3.3) | 10.5 (3.1) | 11.7 (3.4) | > 0.05 | 0.045 |
| IQCODE (SD) | 610 | 83.3 (11.5) | 86.8 (15.5) | 82.0 (9.1) | < 0.001 | < 0.001 |
| The Montreal Cognitive Assessment | 511 | 19.3 (6.8) | 11.4 (6.5) | 21.0 (5.5) | < 0.001 | < 0.001 |
| Hypertension | 747 | 533 (71%) | 145 (71%) | 388 (71%) | > 0.05 | > 0.05 |
| Diabetes mellitus | 747 | 203 (27%) | 71 (35%) | 132 (24%) | > 0.05 | > 0.05 |
| Atrial fibrillation | 748 | 180 (24%) | 76 (37%) | 104 (19%) | 0.014 | < 0.001 |
| Myocardial infarct | 747 | 106 (14%) | 33 (16%) | 73 (13%) | > 005 | > 0.05 |
| Respiratory diseases (0–4) | 747 | 1.0 (1.1) | 1.2 (1.3) | 0,.9 (1.0) | 0.004 | < 0.001 |
| CIRS | ||||||
| Total Score | 747 | 9.4 (4.9) | 11.0 (4.7) | 8.8 (4.9) | < 0.001 | < 0.001 |
| Severity index | 747 | 0.7 (0.4) | 0.8 (0.4) | 0.6 (0.4) | < 0.001 | < 0.001 |
| Comorbidity Index | 747 | 3.5 (1.9) | 4.2 (1.8) | 3.3 (1.9) | < 0.001 | < 0.001 |
| Pneumonia at admission | 750 | 72 (10%) | 41 (20%) | 31 (6%) | < 0.001 | < 0.001 |
| Pneumonia during hospitalization | 750 | 44 (6%) | 23 (11%) | 21 (4%) | 0.039 | < 0.001 |
| Urinary tract infection at admission | 723 | 207 (29%) | 85 (42%) | 122 (22%) | 0.001 | < 0.001 |
| Urinary tract infection during hospitalization | 723 | 44 (6%) | 13 (6%) | 31 (6%) | > 0.05 | > 0.05 |
| Hospitalization (days) | 750 | 11.1 (7.3) | 14.0 (10.6) | 10.0 (5.3) | > 0.05 | < 0.001 |
| Aphasia | 750 | 255 (34%) | 89 (44%) | 166 (30%) | < 0.001 | < 0.001 |
| Neglect | 750 | 94 (13%) | 62 (31%) | 32 (6%) | 0.038 | > 0.05 |
| Vision deficits | 750 | 298 (40%) | 145 (71%) | 153 (18%) | < 0.001 | < 0.001 |
| NIHSS | 750 | 8.5 (7.3) | 13.0 (6.7) | 6.9 (6.8) | < 0.001 | < 0.001 |
| Pre-stroke modified Rankin Scale | 749 | 0.7 (1.4) | 1.3 (1.7) | 0.5 (1.2) | < 0.001 | < 0.001 |
| mRS (7–10 day after admission) | 750 | 2.6 (2.0) | 4.1 (1.6) | 2.1 (1.9) | < 0.001 | < 0.001 |
| Maximal temperature between 1 and 3 day | 750 | 37.1 (0.7) | 37.4 (0.7) | 37.1 (0.7) | < 0.001 | < 0.001 |
| Maximal temperature between 4 and 7 day | 726 | 37.0 (0.7) | 37.2 (0.7) | 36.9 (0.6) | < 0.001 | < 0.001 |
Delirium Rating Scale Revised 98, Cognitive Test for Delirium IQCODE Informant Questionnaire on Cognitive Decline in the Elderly, mRS modified Rankin Scale, NIHSS National Institute of Health Stroke Scale, CIRS The Cumulative Illness Rating Scale