Table 1.

Time course of serum magnesium level, ECG, level of dose reduction of chemotherapy, and supplementation of magnesium

Total number of administrations	Mg sulfate supplementation	Dose reduction	Abnormality on ECG	Serum Mg	CTCAE grade
12	20 mEq	None	No	0.9 mg/dL	2
13	20 mEq	1st level	No	1.0 mg/dL	2
14	20 mEq	1st level	No	0.9 mg/dL	2
15	40 mEq	2nd level	No	0.9 mg/dL	2
16	40 mEq	2nd level	No	0.9 mg/dL	2
17	40 mEq	2nd level	No	0.9 mg/dL	2

Mg magnesium, irinotecan, ECG electrocardiogram, CTCAE Common Terminology Criteria for Adverse Events