Table 2.

Descriptive statistics at different stages of follow-up, where n denotes the number of women observed in each stage (that is, a subset of the previous stage)

Variable	DBT	DM	P value
Screening stage	(n = 14,734)	(n = 14,719)
Age (SD)	59.5 (5.8)	59.5 (5.8)	0.52
Total time, screen reading (s) (SD)	132 (91)	79 (94)	< 0.001
Consensus rate (%)	6.6%	7.6%	< 0.001
Time used at consensus (s) (SD)	170 (106)	124 (124)	< 0.001
Incremental screening costs per woman, DBT (SD)	€8.5 (5.2)		< 0.001
Recall assessment stage	(n = 495)	(n = 625)
Use of additional imaging—DM	81.4%	82.2%	0.72
Use of additional imaging—DBT	11.5%	23.2%	< 0.001
Use of ultrasound	96.4%	97.9%	0.12
Biopsy performed	52.3%	43.7%	< 0.01
Imaging cost (SD)	€50 (90)	€60 (100)	0.13
Biopsy cost (SD)	€240 (290)	€210 (260)	0.10
Total recall costs (SD)	€290 (260)	€270 (230)	0.37
Treatment stage	(n = 272)	(n = 288)
Cancer type: benign tumour	62.1%	67.0%	0.22
Ductal carcinoma in situ	5.9%	6.2%
Locally advanced	1.8%	3.5%
Invasive	30.2%	23.3%
Diagnostic biopsy	28.7%	24.7%	0.28
Any surgery	44.9%	39.6%	0.21
Wedge resection of breast	39.7%	34.7%	0.22
Excision of axillary lymph node	28.3%	23.6%	0.21
Subcutaneous mastectomy	0.4%	1.0%	0.34
Total mastectomy	5.5%	4.5%	0.59
Breast reconstruction with prosthesis	0.7%	1.7%	0.29
Total hospital length of stay (SD)	3.7 (10.1)	2.4 (3.4)	0.42
Radiation therapy	33.1%	25.4%	0.04
Chemotherapy	15.8%	9.4%	0.02
Endocrine treatment	22.1%	18.1%	0.24
Immunotherapy	2.9%	2.8%	0.91
Surgery cost (SD)	€6500 (9300)	€6400 (11,700)	0.25
Radiation therapy cost (SD)	€2000 (2800)	€1500 (2600)	0.04
Chemotherapy cost (SD)	€1300 (3500)	€700 (2500)	0.02
Medication cost (SD)	€900 (4500)	€800 (4100)	0.10
Total treatment costs (SD)	€10,700 (15,600)	€9400 (16,000)	0.16

Treatment stage includes both benign and malignant tumours. Costs are given per woman in the respective stage

DBT digital breast tomosynthesis and synthetic mammography; DM digital mammography