Table 3.
Performance of the top diagnostic miRNA biomarkers.
| miRNA | AUC | Accuracy | 95% CI | Sensitivity | Specificity |
|---|---|---|---|---|---|
| Logistic model on the 2:1 cohort | |||||
| hsa-miR-1-3p_477820_mir | 0,923 | 0,941 | [0.936; 0.946] | 0,938 | 0,943 |
| hsa-miR-144-5p_477914_mir | 0,925 | 0,878 | [0.872; 0.883] | 0,776 | 0,941 |
| hsa-miR-150-5p_477918_mir | 0,937 | 0,825 | [0.818; 0.831] | 0,666 | 0,925 |
| Logistic model on the whole cohort | |||||
| hsa-miR-1-3p_477820_mir | 0,914 | 0,941 | [0.803; 0.993] | 0,929 | 0,95 |
| hsa-miR-150-5p_477918_mir | 0,939 | 0,912 | [0.763; 0.981] | 0,857 | 0,95 |
| hsa-miR-144-5p_477914_mir | 0,925 | 0,882 | [0.725; 0.967] | 0,786 | 0,95 |
AUC values, accuracy, sensitivity, specificity and 95% of confidence intervals are summarized for those miRNAs which were selected for the highest diagnostic performance on the 2:1 cohort (on top) and the whole cohort (below).