Table 3.
Comparative genome analysis of the proteolytic system of L. helveticus LH-2 with L. helveticus CNRZ 32 (abbreviation LAC LHE, accession number CP002081) at the nucleotide level using NCBI microbial genome database and Blast alignment tools.
| Gene (NCBI accession number) | Identity (%) |
|---|---|
| CELL ENVELOPE-ASSOCIATED PROTEINASES | |
| prtH (AAD50643) | 0 |
| prtH2 (DQ826130) | 0 |
| prtH3 (HQ602769) | 4,913/4,914 (99%) |
| prtH4 (HQ602770) | 4,974/4,977 (99%) |
| prtM (DQ826131) | 0 |
| prtM2 (DQ826132) | 903/903 (100%) |
| OLIGOPEPTIDE TRANSPORT | |
| oligopeptide ABC transport protein ATP-binding component OppF2 (AGQ24255.1) | 314/314 (100%) |
| oligopeptide ABC transport protein ATP-binding component OppD2 (AGQ24256.1) | 351/352 (99%) |
| oligopeptide ABC transport protein ATP-binding component OppF1 (AGQ23787.1) | 328/328 (100%) |
| oligopeptide ABC transport protein ATP-binding component OppD1 (AGQ23788.1) | 342/344 (99%) |
| oligopeptide ABC transport protein periplasmic component OppA4 (AGQ24260.1) | 496/510 (97%) |
| oligopeptide ABC transport protein periplasmic component OppA5 (AGQ24261.1) | 538/540 (99%) |
| oligopeptide ABC transport protein ATP-binding component OppB2 (AGQ24258.1) | 309/309 (100%) |
| oligopeptide ABC transport protein permease component OppC2 (AGQ24257.1) oligopeptide ABC transport protein permease component OppC1 (AGQ23785.1) |
269/269 (100%) 285/286 (99%) |
| PEPTIDASES | |
| Oligoendopeptidase pepF (AY365129) | 2,363/2,370 (99%) |
| Oligoendopeptidase pepO (AF019410) | 2,690/2,691 (99%) |
| Oligoendopeptidase pepO2 (DQ826126) | 1,939/1,947 (99%) |
| sialoglycoprotein endopeptidase Ogcp (DQ826107) | 1,050/1,050 (100%) |
| General aminopeptidases pepCE (JF811429) | 1,314/1,314 (100%) |
| General aminopeptidases pepC (HQ602766) | 1,349/1,350 (99%) |
| General aminopeptidases pepN (U08224) | 3,754/3,787 (99%) |
| X-prolyl diaminopeptidase pepX (U22900) | 3,204/3,204 (100%) |
| Proline iminopeptidases pepI (DQ826125) | 885/885 (100%) |
| Proline iminopeptidases pepR (U05214) | 1,259/1,260 (99%) |
| Prolidase pepQ (AF012084) | 2,177/2,181 (99%) |
| Prolidase pepQ2 (DQ826127) | 1,110/1,110 (100%) |
| Dipeptidase pepD (U34257) | 2,244/2,253 (99%) |
| Dipeptidase pepD2 (DQ826122) | 1,422/1,422 (100%) |
| Dipeptidase pepD3 (DQ826123) | 1,424/1,428 (99%) |
| Dipeptidase pepV (AF012085) | 2,402/2,404 (99%) |
| Tripeptidase pepT (DQ826128) | 1,242/1,242 (100%) |
| Tripeptidase pepT2 (DQ826129) | 1,287/1,287 (100%) |
| Glutamyl aminopeptidase pepA (DQ826138) | 1,083/1,083 (100%) |
| Methionine aminopeptidase map (DQ826118) | 828/828 (100%) |
| Pyrrolidone carboxyl peptidase pcp (DQ826121) | 603/603 (100%) |
| SprT-like metallopeptidase sprT (HQ602765) | 470/471 (99%) |
| M16 family metallopeptidase hyp prt2 (DQ826112) | 1,257/1,257 (100%) |
| Membrane alanine aminopeptidase pepM1 (HQ602768) | 1,515/1,515 (100%) |