Table 2. The frequencies of genotypes of the studied substitutions in PDE4B gene in the group of patients with panic disorder (PD) and the control group (Cont) as well as the subgroups.
SNP and genotypes | All samples | Female | Male | ||||
Cont | PD | Cont | PD | Cont | PD | ||
rs502958 | AA | 0.289 | 0.261 | 0.148 | 0.240 | 0.167 | 0.316 |
AT | 0.505 | 0.500 | 0.574 | 0.427 | 0.607 | 0.316 | |
TT | 0.205 | 0.239 | 0.278 | 0.333 | 0.226 | 0.368 | |
rs1040716 | AA | 0.156 | 0.255 | 0.352 | 0.400 | 0.386 | 0.316 |
AT | 0.589 | 0.404 | 0.537 | 0.467 | 0.506 | 0.526 | |
TT | 0.255 | 0.340 | 0.111 | 0.133 | 0.108 | 0.158 | |
rs10454453 | AA | 0.366 | 0.383 | 0.271 | 0.247 | 0.313 | 0.316 |
AC | 0.524 | 0.479 | 0.551 | 0.493 | 0.446 | 0.526 | |
CC | 0.110 | 0.138 | 0.178 | 0.260 | 0.241 | 0.158 | |
n = 192 | n = 94 | n = 108 | n = 75 | n = 84 | n = 19 |