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Microvascular endothelial oxidative stress can be reduced in VCECs in the presence of HSPCs in vitro. (A) Oxidative damage incurred by H2O2 treated vena cava endothelium is reduced following incubation with HSPCs for 72 h (*P < 0.05; n = 4; t-test). (B and C) H2O2 driven ROS generation, measured by DHE staining, is reduced by HSPCs at 72 h (***P < 0.001; n = 3; t-test). Red, DHE stain; Yellow, CFSE-labelled HSPCs. Scale bars represent 100 μm.
