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. 2019 Oct 8;24(19):3625. doi: 10.3390/molecules24193625

Table 2.

Cell viability after treatment of human cancer cell lines and control cell line with ‘standard’ concentration of oligonucleotides, 10 μM. The cell line is listed according to the cell viability after biHD1 treatment. The viability values with less than 70% are in bold. All data could be found in the Supplement Figures S2–S8. In the biHD1-C3 column, * marks the data for the single-modular HD1.

Cell Line Cell Viability, %
biHD1 biHD1-C3 biHD1-T4A, T20 biHD1-5′-∆2G biHD1+Ba
RL-67 34 58 51 100 103
U87 45 104/103 * 94 66 96
HeLa 57 70 91 74 86
HCT116 58 96 105 74 100
MCF7 64 90 102 85 87
mS 77 96 93 93 98
PC3 78 131 91 85 76
hEF 90 70/87 * 95 91 101