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. 2019 Sep 26;24(19):3489. doi: 10.3390/molecules24193489

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Phylogenetic tree of the P-III SVMPs. The amino acid sequences of 22 SVMPs were used for phylogenetic tree construction by the program Mega 5.1. Atr-III from Peruvian Bothrops atrox is marked (♦) and the others P-III class SVMPs: Bi (Bothrops insularis, AF490534); Bothropasin (Bothrops jararaca, AAC61986); Batroxrhagin (Brazilian B. atrox, ALB00542); Jararhagin (B. jararaca, CAA48323); Gh-MPIII (Gloydius halys, AAD02652); Acurhagin (Deinagkistrodon acutus, AAS57937); Acutolysin (Deinagkistrodon acutus, AAD27891); Cd MPIII (Crotalus durissus durissus, ABA42117); Ca-MPIII (Crotalus atrox, A4PBQ9); Cvv-MPIII (Crotalus viridis viridis, ACV83933); Ca-VMPIII (Crotalus atrox, ACV83931); Catrocollastatin (Crotalus atrox, AAC59672); Bl-MPIII (Bothriechis lateralis, AGY49227); Cad MPIII (Crotalus adamanteus, J3S830); leucurolysin-B (Bothrops leucurus, P86092); Da MPIII (Deinagkistrodon acutus, BAO23490); Acl-MPIII (Agkistrodon contortrix laticinctus, ACV83929); Gi-MPIII (Gloydius intermedius, AJI77146); elegantin1A (Protobothrops elegans, BAB69657); Ca-VMPIII (Crotalus adamanteus, AEJ31986); Jerdonitin (Protobothrops jerdonii, AAQ63966); and Gallus gallus ADAM9 was used as the outgroup (NP-001026567).