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. 2019 Sep 17;4(1):e000321. doi: 10.1136/tsaco-2019-000321

Table 1.

Select laboratory data

Timepoint
Variable Group Baseline End of shock
Weight (g) Vehicle 272.±11.4
MC1568 276.3±7.4
ACY1083 279.5±10.0
MC1568+ACY1083 270.5±11.7
VPA 278.0±8.3
Cannulation time (min) Vehicle 13.3±1.7
MC1568 15.0±1.6
ACY1083 15.5±2.3
MC1568+ACY1083 18.5±1.0
VPA 13.5±1.5
MAP (mm Hg) Vehicle 94.9±1.5 50.8±3.5*
MC1568 92.2±5.4 49.1±1.3*
ACY1083 92.7±7.2 53.7±4.2*
MC1568+ACY1083 93.3±4.4 53.8±2.3*
VPA 94.1±4.5 57.9±2.9*
Lactate (mmol/L) Vehicle 1.4±0.1 4.3±1.0*
MC1568 1.5±0.2 4.9±0.6*
ACY1083 1.3±0.1 4.7±0.5*
MC1568+ACY1083 1.2±0.1 4.5±0.3*
VPA 1.3±0.2 4.3±0.6*

*Significant difference compared with the baseline value of the same group (p<0.05).

MAP, mean arterial pressure; VPA, valproic acid.