Table 3.
Average resource use and costs per category at 12-month follow-up (Bootstrap results).
| Category Units | Unit Costs in Euros (€) | Treatment (S53P4) Cohort (n = 17) | Control (PMMA) Cohort (n = 25) | Average Cost Differences | |||
|---|---|---|---|---|---|---|---|
| Average Number | Mean Costs in € | Average Number | Mean COSTS in € | Cost differences | 95% CI | ||
| Hospital costs | |||||||
| Hospitalization | |||||||
| Standard care unit (day) | 642 | 18.8 | 12,146.95 | 29.0 | 18,533.85 | −6497.04 | (−10,375; 2259) |
| Intensive care unit (day) | 2015 | 0.0 | 0 | 0.3 | 622.23 | −622.23 | (−1934; 0) |
| Total hospital costs | 17.9 | 11,882.14 | 29.3 | 19,154.23 | −7272.09 | (−12,339; −2,78) | |
| Surgical costs | |||||||
| General surgery (minutes) | 12.14 | 151.4 | 1841.88 | 222.3 | 2711.22 | −869.34 | (−1475; −253) |
| Orthopaedic surgery (min) | 4.59 | 88.1 | 404.7 | 132.6 | 607.40 | −203.03 | (−342; −69) |
| Average surgical costs | 2205.78 | 3306.72 | −1100.94 | (−1891; −345) | |||
| PICC-line (per placement) | 569.90 | 0.6 | 344.27 | 0.24 | 162.22 | 182.05 | (23; 342) |
| Fluoroscopy (per surgery) | 150.69 | 0.2 | 30.43 | 0.4 | 60.29 | −29.86 | (−66; 6) |
| Total Surgical costs | 2574,71 | 3535.33 | −960.62 | (−1734; −218) | |||
| Material costs | |||||||
| S53P4 BAG (1 cc) | 89 | 22.3 | 2007.20 | n.a. | 0 | 2007.20 | |
| PMMA beads (1 bead) | 6.12 | n.a. | 0.00 | 59.7 | 365.00 | −365.00 | |
| Total material costs | 2012.15 | 372.24 | 1639.91 | (1123; 2.256) | |||
| Imaging costs | |||||||
| X-ray | 49.55 | 4.84 | 240.10 | 9.12 | 450.87 | −211 | (−343; −93) |
| CT | 140/145 | 0.56 | 77.40 | 0.88 | 123.44 | −46 | (−129; −33) |
| MRI | 229/215 | 0.40 | 86.24 | 0.48 | 102.53 | −16 | (−104; 86) |
| FDG PET-CT | 1275.82 | 1.28 | 1620.14 | 0.36 | 460.98 | 1159 | (612; 1685) |
| Scintigraphy | 338.50 | 0.12 | 40.76 | 0.32 | 105.94 | −65 | (−149; 27) |
| Total imaging costs | 1960.63 | 1142.83 | 818 | (208; 1368) | |||
| Blood sample analysis | |||||||
| C-reactive protein | 4.07 | 9.1 | 36.87 | 12.12 | 48.96 | −12 | (−27; 0) |
| Erythrocyte sedimentation | 1.08 | 8.7 | 9.38 | 12.76 | 13.80 | −4 | (−8; −1) |
| Leukocyte count | 1.08 | 6.2 | 6.69 | 12.88 | 13.95 | −7 | (−11; −4) |
| Sodium | 1.79 | 9.08 | 16.26 | 8.40 | 15.03 | 1 | (−6; 8) |
| Potassium | 1.79 | 8.96 | 16.08 | 8.48 | 15.23 | 0.9 | (−7; 8) |
| Creatinine | 1.78 | 9.12 | 16.29 | 8.88 | 15.84 | 0.5 | (−7; 8) |
| Urea | 1.63 | 9.08 | 14.78 | 8.60 | 14.09 | 0.7 | (−6; 8) |
| Alanine aminotransferase | 2.10 | 2.24 | 4.64 | 3.80 | 7.96 | −3 | (−6; 0) |
| Aspartate aminotransferase | 1.95 | 2.20 | 4.31 | 3.76 | 7.32 | −3 | (−5; 0) |
| Gammaglutyltransaminase | 1.96 | 2.24 | 4.38 | 3.68 | 7.23 | −3 | (−6; 0) |
| Haemoglobin/haematocrit | 1,74 | 10.60 | 18.56 | 12.16 | 21.25 | −3 | (−11; 6) |
| Total blood analysis | 148.40 | 179.26 | −31 | (−96; 28) | |||
| Microbiological cultures | |||||||
| Tissue cultures | 67.38 | 3.7 | 246.25 | 2.4 | 159.25 | 87 | (10; 160) |
| Fluid cultures | 55.48 | 1.8 | 102.75 | 4.0 | 220.97 | −118 | (−20; −21) |
| Total microbiology | 346.17 | 381.67 | −36 | (−139; 64) | |||
| Antibiotics | |||||||
| Intravenous (day) | 25.40 | 15.2 | 332.09 | 32.2 | 856.09 | −524 | (−848; −237) |
| Oral (day) | 1.01 | 49.7 | 43.27 | 55.6 | 60.93 | −18 | (−41; 5) |
| Total antibiotics | 346.46 | 873.48 | −527 | (−832; −277) | |||
| Outpatients’ Clinic costs | |||||||
| Visits | 163 | 8.1 | 1327.06 | 8.8 | 1445.51 | −118 | (−424; 202) |
| Total costs | 20,568.31 (SD 1599.37) | 27,141.69 (SD 2410.12) | −6573 | (−12,572; −1295) | |||