Table 1.
Characteristics of Participants in the MDC and MPP
| MPP | MDC | |||||
|---|---|---|---|---|---|---|
| Trait | Controls (N = 496) | Incident T2DM (N = 202) | P | Cohort Without T2DM (N = 3021) | Incident T2DM (N = 402) | P |
| Age, y | 68.7 (±5.9) | 69.3 (±5.7) | 0.31 | 57.5 (±6.0) | 57.8 (±5.8) | 0.25 |
| Sex, % female | 37.2 | 31.4 | 0.16 | 61.0 | 55.0 | 0.023 |
| BMI, kg/m2 | 26.5 (±4.2) | 29.2 (±4.8) | <0.001 | 25.1 (±3.5) | 27.4 (±4.6) | <0.001 |
| Fasting glucose, mmol/L | 5.4 (±0.5) | 6.0 (±0.6) | <0.001 | 4.9 (±0.4) | 5.2 (±0.4) | <0.001 |
| Systolic blood pressure, mm HG | 143 (±21) | 149 (±20) | 0.0030 | 140 (±19) | 146 (±19) | <0.001 |
| HDL cholesterol, mmol/L | 1.42 (±0.43) | 1.27 (±0.38) | <0.001 | 1.43 (±0.31) | 1.28 (±0.37) | <0.001 |
| LDL cholesterol, mmol/L | 3.7 (±0.9) | 3.7 (±1.0) | 0.79 | 4.13 (±1.0) | 4.33 (±1.0) | <0.001 |
| Triglycerides, mmol/L | 1.2 (±0.6) | 1.4 (±0.7) | <0.001 | 1.22 (±1.2) | 1.53 (±1.5) | <0.001 |
Differences in the baseline characteristics between participants with incident T2DM and participants without incident T2DM were investigated via two-sample t test (continuous variables) and Pearson χ2 test (sex).