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. 2019 Aug 30;15:1–6. doi: 10.1016/j.omto.2019.08.007

Figure 2.

Figure 2

CARD9 Function Inhibited CAC Growth through the Activation of Inflammasomes

Recognition of commensal gut fungi, sensed via a CARD9-dependent manner, promoted inflammasome activation and IL-18 maturation, and eventually it suppressed CAC development. (A and B) WT (A) and Card9–/– (B) mice.