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Effects of the three putative YB-1 inhibitors on YB-1 binding to decoy oligonucleotide, tested at a range of concentrations by AlphaScreen assay. Data shown are the mean of two replicates at each compound concentration within single experiment, with error bars indicating range. Results shown here are representative of two independent experiments. (A) RUS0207-A006 (IC50=41 µmol/L). (B) RUS0202-G005 (IC50=27 µmol/L). (C) JK0395-B007 (IC50=25 µmol/L).
