Skip to main content
. 2019 Apr 5;9(5):1061–1077. doi: 10.1016/j.apsb.2019.03.006

Figure 9.

Fig. 9

Toxicity studies after intravenous administration. (A) Body weight changes of mice during antitumor efficacy study (mean ± SD, n = 6). Arrows indicate the time for injection after tumor cells inoculation. *P < 0.05 vs PBS. (B) Effects of different formulations on white blood cells (WBC) counts at the end of test (mean ± SD, n = 5). *P < 0.05 and **P < 0.01 vs PBS; #P < 0.05 vs M-PTX; ▵▵P < 0.01 vs 7pep-M-PTX; □P < 0.05 vs 7pep-M-Combi. (C) Optical microscopy images of H&E staining livers after treated with different formulations. Magnification, 200×. Red circles indicate the necrotic area in livers.