Table 4.
Comparison of different optical coherence tomography analysis between mild cognitive impairment (MCI) and Alzheimer's disease (AD) eyes
| Variables | MCI (N = 51) | AD (N = 12) | P |
|---|---|---|---|
| Average RNFL thickness | 93.7 (12.5) | 99.4 (5.1) | .155 |
| RNFL temporal | 65.9 (9.4) | 70.0 (6.2) | .411 |
| RNFL temporal-superior | 119.5 (16.3) | 115.0 (19.0) | .793 |
| RNFL temporal-inferior | 139.5 (22.0) | 138.7 (10.4) | .774 |
| RNFL nasal | 79.6 (18.3) | 85.2 (14.4) | .653 |
| RNFL nasal-superior | 108.9 (22.1) | 124.3 (22.1) | .060 |
| RNFL nasal-inferior | 109.7 (27.4) | 83.0 (33.71) | .045∗ |
| Average BMO-MRW | 281.9 (49.9) | 326.8 (58.8) | .016∗ |
| BMO-MRW temporal | 207.7 (52.8) | 214.2 (27.6) | .740 |
| BMO-MRW temporal-superior | 272.2 (70.1) | 273.3 (28.8) | .984 |
| BMO-MRW temporal-inferior | 277.6 (69.7) | 324.6 (41.2) | .126 |
| BMO-MRW nasal | 305.5 (55.2) | 383.6 (74.9) | .006∗ |
| BMO-MRW nasal-superior | 322.4 (74.9) | 353.0 (76.3) | .392 |
| BMO-MRW nasal-inferior | 342.2 (61.8) | 375.6 (69.8) | .245 |
| GCL superior | 48.3 (7.1) | 44.3 (14.9) | .174 |
| GCL inferior | 47.1 (8.5) | 44.2 (14.4) | .365 |
| GCL temporal | 42.2 (8.4) | 39.6 (13.4) | .384 |
| GCL nasal | 47.3 (7.8) | 43.3 (14.2) | .185 |
| IPL superior | 39.1 (4.4) | 38.8 (4.1) | .852 |
| IPL inferior | 38.5 (4.5) | 38.8 (2.9) | .890 |
| IPL temporal | 39.6 (4.1) | 39.2 (3.8) | .740 |
| IPL nasal | 39.7 (4.1) | 39.7 (3.3) | .944 |
| ONL superior | 63.3 (11.6) | 63.5 (12.3) | .086 |
| ONL inferior | 60.3 (14.5) | 62.5 (18.4) | .652 |
| ONL temporal | 68.6 (10.5) | 72.9 (7.8) | .203 |
| ONL nasal | 68.2 (15.1) | 68.3 (16.9) | .923 |
NOTE. Data for quantitative variables are shown as mean (standard deviation). Analysis was performed using paired Student's t-test for dependent samples.
Abbreviations: RNFL, retinal nerve fiber layer; GCL, ganglion cell layer; BMO-MRW, Bruch's membrane opening–minimum rim width; IPL, inner plexiform layer; ONL, outer nuclear layer.
∗
P value < .005.