Table 2.
Recovery and matrix effect data.
| Analyte | Recovery (%)a | RSD (%)a | Ion supression (%) ± SD (%) in matrixb |
|---|---|---|---|
| AC-262536 | 83 | 8.9 | 20.1 ± 12.8 |
| Andarine | 89 | 7.9 | 26.2 ± 9.2 |
| Bicalutamide | 85 | 10.6 | 21.5 ± 12.5 |
| BMS-564929 | 99 | 10.9 | 54 ± 6.5 |
| GLPG0492 | 93 | 7.3 | 36.6 ± 8.9 |
| LGD-2226 | 87 | 11.7 | 25.3 ± 15.5 |
| LGD-4033 | 93 | 7.3 | 28.7 ± 14.4 |
| Ly2452473 | 91 | 7.5 | 21.3 ± 14.3 |
| Ostarine | 87 | 8.2 | 9.5 ± 16.2 |
| PF-06260414 | 100 | 11.0 | 39.8 ± 7.2 |
| RAD140 | 92 | 9.0 | 46.0 ± 10.6 |
| S-1 | 87 | 8.9 | 29.1 ± 18.8 |
| S-6 | 81 | 12.0 | 26.9 ± 24.9 |
| S-9 | 82 | 10.2 | 28.9 ± 22.9 |
| S-23 | 83 | 9.0 | 24.6 ± 22.9 |
Recovery was determined by comparing results from fortified samples to those of negative samples spiked post-extraction at the screening target concentration (Cval). Recovery is based on data collected from six analytical runs.
Ion suppression results for urine matrices are based on the analysis of 12 samples from different sources. Values calculated as described in Section 2.6.