Table 2.

Comparing classification performance based on features used

Features used	Sensitivity	Specificity	PPV	NPV	Accuracy
Vasculature features (F1 and F2)	0.74 ± 0.019	0.77 ± 0.006	0.49 ± 0.018	0.91 ± 0.007	0.76 ± 0.008
Texture measures (F3 to F8)	0.68 ± 0.022	0.76 ± 0.007	0.50 ± 0.019	0.87 ± 0.012	0.74 ± 0.010
Combined (7 PCs of F1 to F8)	0.82 ± 0.022	0.86 ± 0.011	0.73 ± 0.025	0.91 ± 0.011	0.85 ± 0.013

NOTE. Performance values were evaluated using different gold standards: cognitive tests (Cog.) and amyloid status (Aβ).

Abbreviations: PPV, positive predictive value; NPV, negative predictive value.