Table 3.
Clinical features of the patients with STRC deletion
| Case | Agea/ Sex | Onset (yr) | Averaged hearing levelb (right/left) | Progression of hearing loss | Vertigo | Allele 1 | Allele 2 |
|---|---|---|---|---|---|---|---|
| 1 | 5/F | 5 | 36.0/40.0 | undetermined | No | Deletion | Deletion |
| 2 | 26/F | 10 | 42.0/40.0 | Yes | No | Deletion | Deletion |
| 3 | 22/F | 6 | 38.0/38.0 | Yes | Yes | Deletion | c.446 T > C, c.4057 C > T |
| 4 | 32/F | 25 | 50.0/45.0 | Yes | Yes | Deletion | c.-28 C > G, c.179 T > C, c.446 T > C c.4842 C > T, c.4878 C > G |
| 5 | 34/M | 17 | 49.0/48.0 | Yes | No | Deletion | c.446 T > C |
| 6 | 54/F | 53 | 62.0/62.0 | undetermined | No | Deletion | No variation |
| 7 | 43/F | 33 | 39.0/34.0 | Yes | No | Deletion | No variation |
aAge at initial visit
bAveraged hearing level means arithmetic value of thresholds in 0.5, 1, 2, and 4 kHz