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Effects of the kinase inhibitors blocking the erinacines A induction associated with DLD-1 cells death. After the indicated treatment for 24 h, the DLD-1 (A) and HCoEpiC cells (B) were stained with FITC-conjugated Annexin-V and PI for flow cytometry analysis, as described in the Materials and Methods section. The percentages presented in each frame depict the apoptotic cells. *P <0.01, as compared with the control group (0.2% DMSO).
