Figure 1.

The Heatmap of the Mutations Detected in CTCs

(A) Detection of mutations in 19 CTCs of metastatic prostate cancer patient 36 by whole-exome sequencing in Lohr et al.’s³² research. (B) Detection of mutations in six CTCs of metastatic prostate cancer patient 10 by whole-exome sequencing in Lohr et al.’s³² research. (C) Detection of mutations in five CTCs of lung cancer patient 1 and mutations in three CTCs of lung cancer patient 2 by single-sell exome sequencing in De Luca et al.’s³⁰ research. (D) Detection of mutations by massive parallel sequencing in three CTCs of colorectal cancer patient 6 in Heitzer et al.’s³¹ research. (E) Detection of mutations by massive parallel sequencing in five CTCs of colorectal cancer patient 26 in Heitzer et al.’s³¹ research. The areas shaded in dark blue represent the mutations were obtained; the blank areas represent underpowered. The mutated genes are listed in the left column.