Table 2.

The 5-step development process for HPV-FRAME.

Step	Action	Timeline
Initial steps	Identify the need for a guideline Review the literature The need for a framework was identified via an expert discussion followed by a comprehensive review of the HPV modelling literature conducted for a 2012 Vaccine Monograph.	2009–2013
Pre-meeting activities	Identify participants •HPV-FRAME information sessions held at IPVC 2014 (Seattle), EUROGIN 2015 (Seville) and IPVC 2015 (Lisbon) •Interested parties asked to sign up to mailing list •Website and mailing list were established Generate a list of items for consideration at the meeting •HPV-FRAME Steering Committee held a workshop at IPVC 2015 (Lisbon), to decide upon the structure of the framework	2014–2015
Meeting – EUROGIN 2016 (Salzburg)	Presentation of draft framework •Dedicated HPV-FRAME session held at EUROGIN – Input from attendees. •Abstracts summarising the scope of each section were posted on website.	2016
Meeting – IPVC 2017 (Cape Town)	Presentation of the framework •Dedicated HPV-FRAME session at IPVC 2017	2017
Publication and post-publication activities	Dissemination •Public consultation on manuscript draft: emailed to interested parties for comment. •Submission to journal •Inform other journal editors Review framework regularly •Set up capacity for comments/input for next revision (via website)	2018 - ongoing