Table 1.

Common Treatment Regimens in the United States for Tularemia and Treatment-Related Complications in Pregnancy

Antibiotic	Pregnancy Category	Category Interpretation (From US FDA)	Distribution	Treatment Complications
Gentamicin	Category D	Evidence of risk	Crosses the placenta	Congenital deafness
Doxycycline	Category D	Evidence of risk	Crosses the placenta	Possible discoloration of teeth and enamel hypoplasia
Ciprofloxacin	Category C	Risk cannot be ruled out	Crosses the placenta	Teratogenicity observed in animal models, not observed in limited human studies
Levofloxacin	Category C	Risk cannot be ruled out	Crosses the placenta	Teratogenicity observed in animal models, not observed in limited human studies
Azithromycin	Category B	No evidence of risk in studies	Crosses the placenta

Abbreviation: FDA, Food and Drug Administration.