Fig. 6.

Increased GM-CSF production is associated with decreased C3aR expression and increased IL-8 production in neutrophils. a–c Representative dot plots and pooled data showing expression of C3aR on neutrophils following incubation with different doses of GM-CSF. d C3aR on healthy neutrophils incubated with sepsis patient plasma before and after blocking with an anti-GM-CSF antibody. e–g Representative dot plots and pooled data showing production of IL-8 in neutrophils following incubation with different doses of GM-CSF. h IL-8 in healthy neutrophils incubated with sepsis patient plasma before and after blocking with anti-GM-CSF antibody. *P < 0.05; **P < 0.01