Table 1.
Clinical characteristics of the enrolled subjects
| HC | SIRS | Sepsis | P-value | |
|---|---|---|---|---|
| Number of subjects | 20 | 20 | 43 | |
| Age (years) | 46.2 ± 9.3 | 45.9 ± 7.4 | 44.9 ± 8.6 | 0.62 |
| Sex (male/female) | 15/5 | 13/7 | 29/14 | 0.76 |
| SOFA score | - | 4.0 ± 1.1 | 9.7 ± 4.1 | < 0.01 |
| WBC (×109/L) | 5.1 ± 2.4 | 17.6 ± 4.2 | 15.9 ± 6.0 | < 0.01 |
| PCT (ng/mL) | - | - | 6.2 ± 3.8 | - |
| Pathogen culture | ||||
| Gram−bacteria | - | - | 24 (55.8%) | - |
| Gram+ bacteria | - | - | 9 (20.9%) | - |
| Fungi | - | - | 3 (7.0%) | - |
| Negative culture | - | - | 7 (16.3%) | - |
| Mechanical ventilation (n) | - | 4 (9.3%) | 17 (39.5%) | 0.21 |
| Mechanical ventilation (days) | - | 1.25 ± 0.4 | 8.1 ± 2.7 | < 0.01 |
| Renal replacement therapy (n) | - | 0 (0%) | 12 (27.9%) | 0.02 |
| ICU stay (days) | - | 2.8 ± 0.7 | 23.5 ± 7.6 | < 0.01 |
| Mortality (nonsurviving/surviving) | - | 0% (0/20) | 34.9% (15/28) | < 0.01 |
Data are shown as number (%) or mean ± SD
SIRS systemic inflammatory response syndrome, SOFA sepsis-related organ failure assessment, WBC white blood cell count, PCT procalcitonin