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. 2019 Aug 7;20(12):1453–1461. doi: 10.1080/15384047.2019.1647058

Figure 5.

Figure 5.

MiR-4784/AHDC1 reversed the modulatory impact of LINC01133 on invasive and migratory potentials and EMT in CC. (a) Confirmation of the overexpression efficiency of AHDC1 in ME-180 and MS751 cells was accomplished by qRT-PCR. (b-c) Post-transfection of indicated plasmids, the growth of ME-180 cells was assessed by CCK-8 and EdU assays. (d) ME-180 cell apoptosis after transfection with certain plasmids was evaluated by caspase-3 activity assay. (e-f) Transwell assay was executed to probe the migration and invasion of ME-180 cells transfected with specific plasmids. (g) Western blot was implemented to examine the effects of LINC01133/miR-4784/AHDC1 pathway on the EMT-associated protein contents. *P < .05, **P < .01.