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Tumor-associated antigen cytotoxic T-cell (TAA-T) products express low levels of exhaustion markers. Exhaustion markers T-cell immunoglobulin and mucin domain–containing-3 (TIM3), programmed cell death 1 (PD1), and cytotoxic T lymphocyte antigen 4 (CTLA4) were at uniformly low levels in TAA-T products as detected by flow cytometry. Lymphocyte-associated gene 3 (LAG3) was higher in products generated for nonresponders compared with responders.
