Of samples that were positive for anti-pegaspargase, shown are the percent positive for anti-PEG and anti–Escherichia
coli asparaginase (L-ASP) at each protocol time point in the Total XVI study. cons, consolidation day 1; d1, induction day 1; d8, induction day 8; d15, induction day 15; w7, continuation week 7; w8, continuation week 8; w9, continuation week 9; w17, continuation week 17; w19, continuation week 19.