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Suggested algorithm for the management of small renal masses (SRMs). Renal mass biopsy (RMB) depicts clinical scenarios in which RMB can be considered. (*) When technically feasible. (†) Benign pathology, chromophobe, papillary type 1, or Fuhrman grade 1 to 2 metastatic renal cell carcinoma (mRCC). AS, active surveillance; CCI, Charlson Comorbidity Index; PN, partial nephrectomy; QOL, quality of life; RCC, renal cell carcinoma; TA, thermal ablation.
