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. 2018 Dec 3;37(3):190–201. doi: 10.1200/JCO.18.01583

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© 2018 by American Society of Clinical Oncology

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FIG A14. — Kaplan-Meier curves of the outcomes in 223 patients with de novo diffuse large B-cell lymphoma (DLBCL) with advanced-stage disease treated with curative intent with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone in the BC Cancer cohort grouped according to double-hit signature (DHITsig) status and cell of origin. (A) Time to progression (TTP). (B) Disease-specific survival (DSS). (C) Progression-free survival (PFS). (D) Overall survival (OS). *P < .001. ABC, activated B-cell-like; GCB, germinal center B-cell-like; HR, hazard ratio; ind, indeterminate; pos, positive.