Fig 1.

Unadjusted mean per-patient per-month spending for all Medicare fee-for-service files from 1 year before to 1 year after an advanced breast cancer diagnosis for patients with de novo stage IV (red) versus recurrent (blue) advanced disease. (A) Total spending. (B) Inpatient (Medicare provider analysis and review) spending. (C) Physician (national claims history) spending. (D) Outpatient (Outpatient standard analytic file) spending. Spending estimates reflect constant 2012 US dollars. Statistical comparisons of spending for de novo versus recurrent patients are presented in Table 2.