Table 1. The concentrations of cytokines in 2D and 3D bladder cancer cell environments after BCG treatment.
| 5637 | T24 | |||||||
|---|---|---|---|---|---|---|---|---|
| 2D | 3D | 2D | 3D | |||||
| untreated | BCG | untreated | BCG | untreated | BCG | untreated | BCG | |
| Cytokine level | ||||||||
| (pg/mL, mean ± SD) | ||||||||
| IL-6 | 195.29 ± 2.30 | 220.66 ± 2.12** | 190.74 ± 2.42 | 198.45 ± 1.61 | 162.69 ± 4.81 | 274.31 ± 6.05** | 128.94 ± 4.66 | 195.21 ± 11.58* |
| IL-12 | 29.62 ± 0.66 | 46.75 ± 0.45** | 25.52 ± 0.99 | 37.44 ± 1.50* | 45.38 ± 1.36 | 60.86 ± 1.77* | 29.33 ± 0.44 | 34.65 ± 1.85 |
| INF-γ | 33.43 ± 1.00 | 40.69 ± 1.05** | 34.50 ± 0.54 | 36.57 ± 1.11 | 46.00 ± 0.23 | 51.54 ± 0.19** | 42.34 ± 0.97 | 44.92 ± 0.34 |
* p < 0.05 and
** p < 0.01
IL: interleukin, INF: interferon