Table 1. Patient characteristics.
| Total (n = 446) |
TPA | No-TPA | |||||
|---|---|---|---|---|---|---|---|
| FO (n = 76) |
UFO (n = 151) |
P | FO (n = 140) |
UFO (n = 79) |
P | ||
| Age (years) | 68.3 (12.6) | 67.4 (10.4) | 68.9 (12.2) | 0.38 |
|
73.5 (13.6) | <0.01 |
| Female | 181 (40.6) | 33 (43.4) | 61 (40.4) | 0.77 |
|
33 (41.8) | 0.75 |
| Current smoker | 117 (26.2) | 17 (22.4) | 38 (26.2) | 0.76 |
|
14 (17.7) | 0.01 |
| Hypertension | 292 (65.5) | 51 (67.1) | 98 (64.9) | 0.86 |
|
57 (72.2) | 0.15 |
| Diabetes mellitus | 98 (22.0) | 16 (21.1) | 33 (21.9) | 1.00 | 34 (24.3) | 15 (19.0) | 0.46 |
| Hyperlipidemia | 76 (17.0) | 16 (21.1) | 19 (12.6) | 0.14 | 30 (21.4) | 11 (13.9) | 0.24 |
| Atrial fibrillation | 156 (35.0) | 29 (38.2) | 64 (42.4) | 0.64 | 33 (23.6) | 30 (38.0) | 0.04 |
| Previous stroke | 77 (17.3) | 5 (6.6) | 30 (19.9) | 0.02 | 22 (15.7) | 20 (25.3) | 0.12 |
| Median initial NIHSS (IQR) | 6 (3–16) | 7 (6–13) | 15 (9–21) | <0.01 | 2 (1–3) | 7 (3–18) | <0.01 |
| Initial SBP | 158.7 (30.2) | 150.8 (29.8) | 158.5 (29.1) | 0.07 | 162.0 (30.7) | 161.1 (31.1) | 0.84 |
| Initial DBP | 87.7 (18.6) | 88.0 (19.9) | 88.1 (18.5) | 0.97 | 89.2 (17.5) | 84.0 (19.4) | 0.05 |
| SBP 12-hr | 141.7 (21.6) | 136.2 (21.1) | 146.1 (22.8) | <0.01 | 137.5 (19.3) | 146.1 (21.4) | <0.01 |
| DBP 12-hr | 79.3 (13.2) | 78.7 (14.6) | 79.7 (13.2) | 0.60 | 79.3 (12.6) | 79.4 (12.8) | 0.98 |
| SBP 24-hr | 140.1 (22.5) | 136.4 (22.2) | 145.1 (21.3) | <0.01 | 135.1 (21.9) | 142.9 (24.1) | 0.02 |
| DBP 24-hr | 78.7 (14.5) | 79.0 (16.5) | 80.2 (12.8) | 0.58 | 77.1 (14.1) | 78.2 (15.9) | 0.58 |
| SBPV | 18.6 (30.4) | 14.4 (30.3) | 13.4 (30.4) | 0.82 | 26.8 (30.5) | 18.2 (27.6) | 0.04 |
| DBPV | 9.0 (19.7) | 9.0 (19.2) | 7.9 (20.5) | 0.69 | 12.1 (19.2) | 5.8 (18.9) | 0.02 |
| Etiological subtypes (LAA/CE/SA/SOD) | 15/31/7/3 | 44/53/6/6 | 0.34 | 24/38/31/5 | 19/20/7/5 | 0.08 | |
| Posterior circulation stroke | 76 (17.0) | 7 (9.2) | 22 (14.6) | 0.35 | 37 (26.4) | 10 (12.7) | 0.03 |
| Antihypertensive agents within 24-hr | 48 (10.8) | 5 (6.6) | 33 (21.9) | <0.01 | 5 (3.6) | 5 (6.3) | 0.55 |
| Progressive neurological deficit | 106 (23.8) | 7 (9.2) | 65 (43.0) | <0.01 | 5 (3.6) | 29 (36.7) | <0.01 |
| Symptomatic HT | 18 (4.0) | 0 (0.0) | 16 (10.6) | <0.01 | 1 (0.7) | 1 (1.3) | 1.00 |
Values are presented as n (%) or mean (SD), unless otherwise stated. IQR, interquartile range; SBP, systolic blood pressure; DBP, diastolic blood pressure; 12-hr, 12 hours after admission; 24-hr, 24 hours after admission; SBPV, systolic blood pressure variation for the first 24 hours; DBPV, diastolic blood pressure variation for the first 24 hours; NIHSS, National Institute of Health Stroke Scale; HT, hemorrhagic transformation.