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. 2019 Oct 22;14(10):e0223966. doi: 10.1371/journal.pone.0223966

Table 3. Index and household contact characteristics in Brazil and Ugandan populations.

Results are shown overall and by TST status. Statistical significance is determined using logistic regression models fit with GEE.

Brazil Uganda
Overall
(N = 838)
Infected (N = 609) Not infected (N = 229) Overall (N = 1153) Infected (N = 829) Not infected (N = 324)
Index Case Characteristics
Female 281(33.5) 164(35.4) 77(29.1) 565 (49.0) 401 (48.4) 164 (50.6)
Age, mean (SD) 35.7 (13.4) 35.1 (13.4) 37.1 (13.2) 33.0 (9.0) 32.8 (9.2) 33.4 (8.6)
Karnofsky Score 𢉤 70 42 (5.0) 21 (3.5) 21(9.2)a N/A
AFB Smear
1+ N/A N/A N/A 86 (7.5) 43 (5.2) 43 (5.2)
2+ 168(20.0) 112(18.4) 56(24.5) 143 (12.4) 81 (10.0) 62 (19.1)
3+ 670 (80.0) 497(81.6) 173(75.5)a 924 (80.1) 705 (85.0) 219 (67.6)d
Culture positive N/A 1131 (98.1) 816 (98.4) 315 (97.2) b
Extent of Disease
Normal/ Min 49(5.9) 34 (5.6) 15 (6.6)d 159 (13.8) 93 (11.2) 66 (20.5)
Moderate 406(49.2) 276 (46.1) 130 (57.3) 385 (33.5) 263 (31.8) 122 (37.9)
Advanced 371(44.9) 289 (48.2) 82 (36.1) 605 (52.7) 471 (57.0) 134 (41.6) d
Missing 12 10 2 3 2 2
Cavitations present 615(74.5) 469 (78.3) 146 (64.3)d 633 (54.9) 499 (60.2) 134 (41.4) d
Missing 12 10 2 0 0 0
Co-prevalent case(s)* 53 (6.3) 34 (5.6) 19 (8.3) 161 (14.0) 123 (14.8) 38 (11.7)
Household Contact Characteristics
Age (years)
Mean(SD) 26.1(19.5) 27.2(19.1) 22.9(20.2) 14.7 (12.9) 15.9 (13.4) 11.7 (11.2)
0–4 74 (8.8) 45 (7.4) 29 (12.7) 249 (21.6) 155 (18.7) 94 (29.0)
5–14 231 (27.6) 148 (24.3) 83 (36.2) 459 (39.8) 325 (39.2) 134 (41.4)
15+ 533 (63.6) 416 (68.3) 117 (51.1)d 445 (38.6) 349 (42.1) 96 (29.6)d
Female 473(56.4) 351(57.6) 122(53.3)a 644 (55.9) 471 (56.8) 173 (53.4)
Share room with index case 204 (24.3) 165(27.1) 39 (17.0)a 693 (60.8) 504 (61.8) 188 (58.4)
Missing 15 13 2
Smoker 194 (23.3) 159(26.4) 35 (15.3)a 68 (5.9) 55 (6.7) 13 (4.0) a
Missing 7 7 0 1 1 0
BCG Scar 686(84.7) 500(84.7) 186(84.5) 845 (73.4) 590 (71.3) 255 (78.7) d
Missing 28 19 9 1 1 0
More than 3 people per room 37 (4.4) 21 (23.5) 16 (7.0) 337 (29.2) 239 (28.8) 98 (30.2)

a 0.10 < p 𢉤 0.20

b 0.05 < p 𢉤 0.10

c 0.01 < p 𢉤 0.05

d p 𢉤 0.01

*77 households had at least one co-prevalent case in Uganda, found of whom had 2 co-prevalence cases.