FIG 3.

CbsR12 production and growth effects on C. burnetii infecting THP-1 cells. (A) Growth curves for MB-WT, MB-cbsR12, and MB-cbsR12-Comp in THP-1 cells as determined by qPCR. The 0-dpi time point refers to the inoculum. Values represent means ± the SEM from three technical replicates. The data are representative of three independent experiments with consistent and indistinguishable results. (B) Cbsr12 production over time for MB-WT, MB-cbsR12, and MB-cbsR12-Comp infecting THP-1 cells, as determined by qRT-PCR. Values represent means ± the SEM from three independent determinations.