TABLE 1.
Top ten expressed genes across various C. burnetii growth conditions, ranked
| Rank | Gene, RNA, or region (tpm)a
|
||||
|---|---|---|---|---|---|
| ACCM-2* LCV (3 dpi) | ACCM-2* SCV (21 dpi) | Vero LCV (3 dpi) | Vero SCV (21 dpi) | THP-1 LCV (3 dpi) | |
| 1 | tmRNA (104,383) | tmRNA (4,430) | tmRNA (153,422) | tmRNA (22,500) | tmRNA (128,928) |
| 2 | CBU_1183 (32,842) | Intergenic (2,632) | CbsR12 (79,870) | CbsR12 (8,521) | RNase P RNA (63,637) |
| 3 | CBU_0307 (13,902) | CBU_1538 (2,133) | RNase P RNA (25,715) | CBU_0089a (8,012) | CbsR12 (33,331) |
| 4 | CBU_1224a (11,023) | Intergenic (1,977) | CBU_0089a (13,882) | CBU_2034 (4,375) | 6S RNA (22,540) |
| 5 | RNase P RNA (10,3923) | tRNA (1,902) | CbsR1 (11,445) | CBU_1170 (3,704) | CBU_0456 (17,603) |
| 6 | CBU_0311 (7,544) | CBU_0183 (1,593) | CBU_0718 (10,370) | CBU_0718 (3,703) | CBU_0474 (16,267) |
| 7 | CBU_0474 (7,120) | Intergenic (1,543) | CBU_1932 (9,734) | CBU_1280a (3,522) | CBU_1183 (13,349) |
| 8 | Intergenic (6,928) | CBU_0157 (1,390) | CBU_1272 (9,011) | RNase P RNA (3,429) | CBU_0307 (12,753) |
| 9 | CBU_0306 (6,666) | Intergenic (1,340) | CBU_0711 (5,530) | Intergenic (3,340) | CBU_0311 (12,146) |
| 10 | CbsR12 (3,522) | Intergenic (1,203) | CBU_1170 (4,633) | CBU_1272 (3,134) | CBU_0473 (11,449) |
a
Genes as annotated for RSA493 (NCBI accession no. NC_002971.4) are listed, with the corresponding transcripts per million (tpm). *, ACCM-2 is an axenic growth medium (37). CbsR12 genes are indicated in boldface. n = 2 biological replicates per condition.