TABLE 4.

Oxidative stress and the SOS response are activated in P. aeruginosa biofilms treated with ciprofloxacin relative to untreated biofilms^a

Activityb	P value for association with differential gene expression in biofilms
	Upregulation	Downregulation
Peroxide stress	10−14	0.33
SOS response	10−5	1.00
Stationary phase	1.00	10−15
HSL quorum sensing	1.00	10−15
Virulence factors	1.00	10−14
Zn limitation	1.00	10−13
Oxygen limitation	1.00	10−6
Phenazine biosynthesis	1.00	10−6
Fe limitation	0.94	10−5

^aBased on gene set enrichment analysis.

^bHSL, homoserine lactone.