Table 1. Clinical data on endoscopic negative pressure therapy (ENPT) for transmural duodenal defects with open-pore polyurethane foam drainage (OPD) and open-pore film drainage (OFD).
| Patient age (y); male (m)/female (f) | Initial diagnosis/initial surgical treatment | Type of transmural defect treated | Open-pore drainage type | Variants of ENPT used | Endoscopic technique used for drainage placement | Duration (days) | Changes of open-pore drain (number) | Success, healing of duodenal defect |
| 43 y; M | Iatrogenic perforation After endoscopic dilatation of a stenosis/ surgical closure with suture and stricturoplasty (course of ENPT is shown in video) | Suture rupture | OPD | IL | Push | 7 | 0 | Yes |
| 60 y; F 9 | Iatrogenic perforation of an operative drain | Iatrogenic perforation | OPD | IL | Push | 7 | 1 | Yes |
| 74y; F | Surgical papillectomy | Suture rupture | OPD | IL | Push | 13 | 2 | Yes, patient died 1 week after end of ENPT |
| 64 y; F | Perforated duodenal ulcer/ surgical closure with suture | Suture rupture | OPD | IC | Intraoperative rendezvous | 11 | 0 | Yes |
| 76 y; F | Perforated duodenal ulcer/ surgical closure with suture | Suture rupture | OPD | IC | Push | 13 | Yes | |
| 80 y; F | Perforated duodenal ulcer/ surgical closure with suture | Suture rupture | OPD | IL | Push, pull-through | 11 | 3 | Yes, patient died 1 month after end of ENPT |
| 61 y; F | Perforated duodenal ulcer/ surgical closure with suture | Suture rupture | OFD, OPD | IL | Push | 19 | 3 | Yes |
| 80 y; F 11 | Iatrogenic perforation typ 2 while ERCP/ diagnostic laparoscopy | Iatrogenic perforation | OFD | IL | Push | 6 | 1 | Yes |
| 71 y; M | Perforated duodenal ulcer: surgical closure with suture | Suture rupture | OPD | IL | Push | 11 | 2 | Yes |
| 53 y; M 12 | Perforated duodenal ulcer/ surgical closure with suture | Suture rupture | OFD, OPD | IL | Pull-through | 14 | 3 | Yes |
| 61 y; M 13 | Perforated duodenal ulcer/ Billroth-1 gastro-jejunostomy | Anastomotic leakage | OFD, OPD | IL/IC | Push, Pull-through | 24 | 5 | Yes |
| 11 Patients 43 – 80 y; 4 × M/7 × F | 8 × Suture rupture 1 × Iatrogenic perforation (ERCP) 1 × Iatrogenic perforation of operative drain 1 × Anastomotic leakage | 7 × OPD 1 × OFD 3 OPD/OFD | 9 × IL 1 × IC 1 × IL/IC | 7 × Push 2 × Push and pull-through 1 × Pull-through 1 × Intraoperative rendevous | m = 11 (7 – 24) | 0 – 5 | 11/11, 2 patients died 1week/ 1 month after ENPT |
ENPT (endoscopic negative pressure therapy); OPD (open-pore polyurethane foam drainage); OFD (open-pore film drainage); IL (intraluminal); IC (intracavitary); ERCP (endoscopic retrograde cholangiopancreatography)