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. 2019 Jul 4;36(11):2591–2603. doi: 10.1093/molbev/msz158

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© The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2. — Positive selection scans for adaptation to high altitude hypoxia. Horses living at high altitude (QT) are compared with lowland controls (NC and SW). The population genetic differentiation F_ST values (A), the nucleotide diversity θ_π ratios (θ_π-LL/θ_π-QT) (B) and the transformed heterozygosity score ZH_P (C) are calculated within 100 kb sliding windows (step size = 15 kb). The significance threshold of selection signature was arbitrarily set to top 5% percentile outliers for each individual test and is indicated with red horizontal dashed lines. The black horizontal dashed lines display the top 1% quantile.